Learn how MaculaPM® Works
Daytime
During the day, the eye is exposed to light and environmental stress.
Nighttime
At night, it shifts into a period of maintenance and renewal.
The RPE Layer
The retinal pigment epithelium continues to process photoreceptor material and maintain cellular balance.
Healthy vision depends on more than antioxidants
L-DOPA and the GPR143 receptor
L-DOPA is the only known endogenous ligand for GPR143 — a receptor expressed in the retinal pigment epithelium. MaculaPM® is formulated around this signaling pathway, which standard eye supplements do not address.*
Formulated for nighttime biology
The eye performs its most important maintenance and renewal processes at night. MaculaPM® is designed as a once-nightly formula to align with this circadian cycle — not as a general daily supplement.*
University of Arizona research lineage
The formulation strategy reflects decades of research in ophthalmology, retinal biology, and macular health from the University of Arizona. Licensed through Tech Launch Arizona. Backed by US patents 11,969,401 and 9,173,862.*
Meet the researchers behind MaculaPM®
unlike traditional antioxidant-only eye supplements. MaculaPM® takes a broader approach by incorporating L-DOPA - a potent regulator of eye health by signaling the GPR143 receptor - and melatonin, which supports circadian timing.
Patented Formula
backed by US patents 11,969,401 and 9,173,862
